Hycamtin Intravenous and Bleeding disorders
Result of checking the interaction of drug Hycamtin Intravenous and disease Bleeding disorders for safety when used together.
When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.
Consumer:Topotecan induces myelosuppression. Severe thrombocytopenia (< 25,000/mm3) has been reported during topotecan therapy. Patients should be instructed to immediately report any signs or symptoms suggesting bleeding such as petechiae, purpura, hematuria, or melena. Close clinical monitoring of hematopoietic function is recommended. Therapy with topotecan should not be initiated in patients with platelet counts < 100,000/mm3. Subsequent courses of topotecan should be withheld until platelet counts exceed 100,000/mm3.
- "Product Information. Hycamtin (topotecan)." SmithKline Beecham, Philadelphia, PA.
Generic Name: topotecan
Brand Name: Hycamtin
Synonyms: Hycamtin (oral/injection), Hycamtin