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Humatin and GI inflammation

Result of checking the interaction of drug Humatin and disease GI inflammation for safety when used together.

Check result:

Humatin <> GI inflammation

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Like other aminoglycosides, paromomycin is potentially oto- and nephrotoxic. While it is poorly absorbed from the gastrointestinal tract, significant systemic absorption may occur if intestinal mucosal integrity is compromised. Therapy with paromomycin should be administered cautiously in patients with inflammatory or ulcerative gastrointestinal diseases because of the potential for enhanced absorption of the drug.

References:

Boston Collaborative Drug Surveillance Program "Drug-induced deafness." JAMA 224 (1973): 515-6
Kunin CM "Nephrotoxicity of antibiotics." JAMA 202 (1967): 204-8
Berk DP, Chalmers T "Deafness complicating antibiotic therapy of hepatic encephalopathy." Ann Intern Med 73 (1970): 393-6
"Product Information. Humatin (paromomycin)." Parke-Davis, Morris Plains, NJ.

Humatin

Generic Name: paromomycin

Brand Name: Humatin, Paromycin

Synonyms: Humatin (Oral)

What is Humatin?