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Hemangeol and Diabetes

Result of checking the interaction of drug Hemangeol and disease Diabetes for safety when used together.

Check result:

Hemangeol <> Diabetes

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Beta-adrenergic receptor blocking agents (aka beta-blockers) may mask symptoms of hypoglycemia such as tremors, tachycardia and blood pressure changes. In addition, the nonselective beta-blockers (e.g., propranolol, pindolol, timolol) may inhibit catecholamine-mediated glycogenolysis, thereby potentiating insulin-induced hypoglycemia and delaying the recovery of normal blood glucose levels. Since cardioselectivity is not absolute, larger doses of beta-1 selective agents may demonstrate these effects as well. Therapy with beta-blockers should be administered cautiously in patients with diabetes or predisposed to spontaneous hypoglycemia.

References:

"Product Information. Kerlone (betaxolol)." Searle, Skokie, IL.
"Product Information. Lopressor (metoprolol)." Novartis Pharmaceuticals, East Hanover, NJ.
"Product Information. Inderal (propranolol)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
"Product Information. Zebeta (bisoprolol)." Lederle Laboratories, Wayne, NJ.
"Product Information. Cartrol (carteolol)." Abbott Pharmaceutical, Abbott Park, IL.
Grimaldi A, Bennett P, Delas B, et al "Beta-blockers and hypoglycaemia: assessment of cardioselective and intrinsic sympathomimetic properties in relation to severity of hypoglycaemia." Curr Ther Res Clin Exp 36 (1984): 361-73
"Product Information. Sectral (acebutolol)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
"Product Information. Blocadren (timolol)." Merck & Co, Inc, West Point, PA.
"Product Information. Trandate (labetalol)." Glaxo Wellcome, Research Triangle Park, NC.
"Product Information. Visken (pindolol)." Sandoz Pharmaceuticals Corporation, East Hanover, NJ.
Darga LL, Hakim MJ, Lucas CP, Franklin BA "Comparison of the effects of guanadrel sulfate and propranolol on blood pressure, functional capacity, serum lipoproteins and glucose in systemic hypertension." Am J Cardiol 67 (1991): 590-6
Velde TM, Kaiser FE "Ophthalmic timolol treatment causing altered hypoglycemic response in a diabetic patient." Arch Intern Med 143 (1983): 1627
Giugliano D, Acampora R, Marfella R, DeRosa N, Ziccardi P, Ragone R, DeAngelis L, DOnofrio F "Metabolic and cardiovascular effects of carvedilol and atenolol in non-insulin-dependent diabetes mellitus and hypertension - A randomized, controlled trial." Ann Intern Med 126 (1997): 955-9
"Product Information. Levatol (penbutolol)." Reed and Carnrick, Jersey City, NJ.
"Product Information. Brevibloc (esmolol)." DuPont Pharmaceuticals, Wilmington, DE.
"Product Information. Coreg (carvedilol)." SmithKline Beecham, Philadelphia, PA.
"Product Information. Normodyne (labetalol)." Schering Laboratories, Kenilworth, NJ.
"Product Information. Tenormin (atenolol)." ICN Pharmaceuticals Inc, Cost Mesa, CA.
"Product Information. Corgard (nadolol)." Bristol-Myers Squibb, Princeton, NJ.
Uusitupa M, Aro A, Pietikainen M "Severe hypoglycaemia caused by physical strain and pindolol therapy." Ann Clin Res 12 (1980): 25-7
"Product Information. Betapace (sotalol)." Berlex, Richmond, CA.