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Guaifen DAC and BPH

Result of checking the interaction of drug Guaifen DAC and disease BPH for safety when used together.

Check result:
Guaifen DAC <> BPH
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Sympathomimetic agents may cause or worsen urinary difficulty in patients with prostate enlargement due to smooth muscle contraction in the bladder neck via stimulation of alpha-1 adrenergic receptors. Therapy with sympathomimetic agents should be administered cautiously in patients with hypertrophy or neoplasm of the prostate.

References:
  • Williams DM "Phenylpropanolamine hydrochloride" Am Pharm NS30 (1990): 47-50
  • "Product Information. Sudafed (pseudoephedrine)." Glaxo Wellcome, Research Triangle Park, NC.
  • Covington TR, Lawson LC, Young LL, eds. "Handbook of Nonprescription Drugs. 10th ed." Washington, DC: American Pharmaceutical Association (1993):
Guaifen DAC

Generic Name: codeine / guaifenesin / pseudoephedrine

Brand Name: Ambifed CD, Biotussin DAC, Cheratussin DAC, Guaifen DAC, Lortuss EX, Maxifed-G CD, Nucofed Pediatric Expectorant, Tricode GF, Tusnel C, Virtussin DAC, Virtussin DAC

Synonyms: n.a.

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