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Gloperba and Renal dysfunction

Result of checking the interaction of drug Gloperba and disease Renal dysfunction for safety when used together.

Check result:

Gloperba <> Renal dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Colchicine is significantly excreted in urine in healthy subjects. Clearance of colchicine is decreased in patients with impaired renal function. Colchicine dosing must be individualized according to the patient's renal function. Caution must be exercised when colchicine therapy is instituted in these patients. Monitoring creatinine function is recommended in patients on long term therapy.

References:

"Product Information. Colchicine (colchicine)." Lilly, Eli and Company, Indianapolis, IN.
Wallace SL, Singer JZ, Duncan GJ, Wigley FM, Kuncl RW "Renal function predicts colchicine toxicity: guidelines for the prophylactic use of colchicine in gout." J Rheumatol 18 (1991): 264-9
Said R, Hamzeh Y, Tarawneh M, el-Khateeb M, Abdeen M, Shaheen A "Rapid progressive glomerulonephritis in patients with familial Mediterranean fever." Am J Kidney Dis 14 (1989): 412-6
Older SA, Finbloom DS, Pezeshkpour GH "Colchicine myoneuropathy and renal dysfunction." Ann Rheum Dis 51 (1992): 1343-4

Gloperba

Generic Name: colchicine

Brand Name: Colcrys, Mitigare

Synonyms: n.a.

What is Gloperba?