Drug search by name

Ganciclovir (Systemic) and Renal dysfunction

Result of checking the interaction of drug Ganciclovir (Systemic) and disease Renal dysfunction for safety when used together.

Check result:

Ganciclovir (Systemic) <> Renal dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Ganciclovir is primarily eliminated by the kidney. Patients with renal impairment may be at greater risk for toxicity from ganciclovir due to decreased drug clearance. Therapy with ganciclovir should be administered cautiously in these patients at reduced dosages. Serum creatinine values should be monitored frequently, and the dosing further adjusted or discontinued accordingly.

References:

Lake KD, Fletcher CV, Love KR, et al "Ganciclovir pharmacokinetics during renal impairment." Antimicrob Agents Chemother 32 (1988): 1899-900
Sommadossi JP, Bevan R, Ling T, et al "Clinical pharmacokinetics of ganciclovir in patients with normal and impaired renal function." Rev Infect Dis 10 (1988): s507-14
"Product Information. Cytovene (ganciclovir)." Genentech, South San Francisco, CA.

Ganciclovir (Systemic)

Generic Name: ganciclovir

Brand Name: Cytovene

Synonyms: Ganciclovir (injection)

What is Ganciclovir (Systemic)?