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Gabapentin Tablets (PHN) and Renal dysfunction

Result of checking the interaction of drug Gabapentin Tablets (PHN) and disease Renal dysfunction for safety when used together.

Check result:

Gabapentin Tablets (PHN) <> Renal dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Gabapentin is primarily eliminated unchanged by the kidney. Therapy with gabapentin should be administered cautiously in patients with impaired renal function. Dosage adjustments and titration should be made in accordance with product package labeling and individual patient response.

References:

Vollmer KO, von Hodenberg A, Kolle EU "Pharmacokinetics and metabolism of gabapentin in rat, dog and man." Arzneimittelforschung 36 (1986): 830-9
Mclean MJ "Clinical pharmacokinetics of gabapentin." Neurology 44 (1994): 17-22
"Product Information. Neurontin (gabapentin)." Parke-Davis, Morris Plains, NJ.
Blum RA, Comstock TJ, Sica DA, Schultz RW, Keller E, Reetze P, Bockbrader H, Tuerck D, Busch JA, Reece PA, et al "Pharmacokinetics of gabapentin in subjects with various degrees of renal function." Clin Pharmacol Ther 56 (1994): 154-9

Gabapentin Tablets (PHN)

Generic Name: gabapentin

Brand Name: Gralise, Horizant, Neurontin, Gabarone

Synonyms: Gabapentin

What is Gabapentin Tablets (PHN)?