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Floxuridine Injection and Myelosuppression

Generic Name: floxuridine
Dosage Forms: n.a.
Other Brand Names: FUDR

Result of checking the interaction of drug Floxuridine Injection and disease Myelosuppression for safety when used together.

Check result:

Floxuridine Injection <> Myelosuppression

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of floxuridine (FUDR) is contraindicated in patients with bone marrow suppression. FUDR induces myelosuppression at recommended dosages. Therapy with FUDR should be administered cautiously in patients who have had prior high-dose pelvic irradiation or alkylating agents or who have widespread metastatic tumor involvement of the bone marrow. Patients should be instructed to immediately report any signs or symptoms suggesting bone marrow suppression such as fever, sore throat, local infection, or bleeding. Close clinical monitoring of hematopoietic function is recommended and therapy should be withheld if platelet counts falls below 100,000/mm3 and/or white blood cell (WBC) counts falls below 3500/mm3 or a rapid fall in WBC is noted.

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