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Alkeran (Melphalan Injection) and Renal dysfunction

Result of checking the interaction of drug Alkeran (Melphalan Injection) and disease Renal dysfunction for safety when used together.

Check result:
Alkeran (Melphalan Injection) <> Renal dysfunction
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The incidence of myelosuppression, particularly during IV administration of melphalan, is increased in patients with a BUN > 30 mg/dl. Therapy with melphalan should be administered cautiously and initiated at a reduced dosage in patients with moderate to severe renal impairment. Clinical monitoring of renal function is recommended.

References:
  • "Product Information. Alkeran Tablets (melphalan)." Glaxo Wellcome, Research Triangle Pk, NC.
Alkeran (Melphalan Injection)

Generic Name: melphalan

Brand Name: Alkeran, Alkeran IV, Evomela

Synonyms: Alkeran (Injection), ALKERAN

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