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Felbamate and Renal dysfunction

Result of checking the interaction of drug Felbamate and disease Renal dysfunction for safety when used together.

Check result:

Felbamate <> Renal dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Felbamate is partially eliminated by the kidney as unchanged drug (approximately 40% to 50% of absorbed dose). The plasma clearance of felbamate may be decreased and the half-life prolonged in patients with impaired renal function. Therapy with felbamate should be administered cautiously in patients with renal impairment.

References:

Wilensky AJ, Friel PN, Ojemann LM, Kupferberg HJ, Levy RH "Pharmacokinetics of W-554 (ADD 03055) in epileptic patients." Epilepsia 26 (1985): 602-6
"Product Information. Felbatol (felbamate)." Wallace Laboratories, Cranbury, NJ.

Felbamate

Generic Name: felbamate

Brand Name: Felbatol

Synonyms: n.a.

What is Felbamate?