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Ethosuximide Capsules and Renal/liver disease

Result of checking the interaction of drug Ethosuximide Capsules and disease Renal/liver disease for safety when used together.

Check result:

Ethosuximide Capsules <> Renal/liver disease

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Succinimide anticonvulsants have produced morphological and functional changes in the liver of animals. In humans, abnormalities in liver and renal function studies have been reported. Therapy with succinimide anticonvulsants should be administered with extreme caution in patients with known hepatic or renal diseases. Periodic urinalysis and liver function tests are recommended for all patients treated with these drugs.

References:

"Product Information. Milontin (phensuximide)." Parke-Davis, Morris Plains, NJ.
"Product Information. Zarontin (ethosuximide)." Parke-Davis, Morris Plains, NJ.
"Product Information. Celontin Kapseals (methsuximide)." Parke-Davis, Morris Plains, NJ.
Coulter DL "Ethosuximide-induced liver dysfunction." Arch Neurol 40 (1983): 393-4
Silverman SH, Gribetz D, Rausen AR "Nephrotic syndrome associated with ethosuccimide." Am J Dis Child 132 (1978): 99
Korinthenberg R, Wehrle L, Zimmerhackl LB "Renal tubular dysfunction following treatment with anti-epileptic drugs." Eur J Pediatr 153 (1994): 855-8

Ethosuximide Capsules

Generic Name: ethosuximide

Brand Name: Zarontin

Synonyms: Ethosuximide

What is Ethosuximide Capsules?