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Ethacrynic Sodium Injection and Diabetes

Result of checking the interaction of drug Ethacrynic Sodium Injection and disease Diabetes for safety when used together.

Check result:

Ethacrynic Sodium Injection <> Diabetes

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Loop diuretics may cause hyperglycemia, glycosuria, and alterations in glucose tolerance tests. Rarely, precipitation of diabetes mellitus has been reported. Therapy with loop diuretics should be administered cautiously in patients with diabetes mellitus, glucose intolerance, or a predisposition to hyperglycemia. Patients with diabetes mellitus should be monitored more closely during therapy, and their antidiabetic regimen adjusted accordingly.

References:

Domenet JG "Diabetogenic effect of oral diuretics." Br Med J 3 (1968): 188
"Product Information. Edecrin (ethacrynic acid)." Merck & Co, Inc, West Point, PA.
Dimitriadis G, Tegos C, Golfinopoulou L, Roboti C, Raptis S "Furosemide-induced hyperglycaemia - the implication of glycolytic kinases." Horm Metab Res 25 (1993): 557-9
Andersen OO, Persson I "Carbohydrate metabolism during treatment with chlorthalidone and ethacrynic acid." Br Med J 2 (1968): 798-801
Chaudhuri ML, Catania J "A comparison of the effects of bumetanide (Burinex) and frusemide on carbohydrate metabolism in the elderly." Br J Clin Pract 42 (1988): 427-9
Gray GM "Drugs, malnutrition, and carbohydrate absorption." Am J Clin Nutr 26 (1973): 121-4
"Product Information. Bumex (bumetanide)." Roche Laboratories, Nutley, NJ.
"Product Information. Demedex (torsemide)." Boehringer Mannheim, Gaithersburg, MD.
"Product Information. Lasix (furosemide)." sanofi-aventis , Bridgewater, NJ.
Coni NK, Gordon PW, Mukherjee AP, Read PR "The effect of frusemide and ethacrynic acid on carbohydrate metabolism." Age Ageing 3 (1974): 85-90

Ethacrynic Sodium Injection

Generic Name: ethacrynic acid

Brand Name: Edecrin, Edecrin Sodium, Sodium Edecrin

Synonyms: Ethacrynic acid, Ethacrynic Acid

What is Ethacrynic Sodium Injection?