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Esketamine and Hepatic impairment

Result of checking the interaction of drug Esketamine and disease Hepatic impairment for safety when used together.

Check result:

Esketamine <> Hepatic impairment

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Esketamine has not been studied in patients with severe hepatic impairment (Child-Pugh class C). Use in this population is not recommended. Additionally, the mean esketamine AUC and t1/2 values were higher in patients with moderate hepatic impairment compared to those with normal hepatic function. Patients with moderate hepatic impairment may need to be monitored for adverse reactions for a longer period of time.

Esketamine

Generic Name: esketamine

Brand Name: Spravato

Synonyms: Esketamine (nasal)

What is Esketamine?