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Escitalopram Oral Solution and Renal dysfunction

Result of checking the interaction of drug Escitalopram Oral Solution and disease Renal dysfunction for safety when used together.

Check result:

Escitalopram Oral Solution <> Renal dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Citalopram (racemic) and escitalopram (the more pharmacologically active S-enantiomer) are extensively metabolized and only small amounts are excreted unchanged in the urine. No dosage adjustments are necessary in patients with mild to moderate renal impairment, as the oral clearance of citalopram has been shown to decrease only modestly (17%) in these patients compared to those with normal renal function. There is no information on the pharmacokinetics of citalopram or escitalopram in patients with severe renal impairment (CrCl < 20 mL/min). Therapy with these agents should be administered cautiously in such patients.

References:

"Product Information. Celexa (citalopram)." Forest Pharmaceuticals, St. Louis, MO.
"Product Information. Lexapro (escitalopram)." Forest Pharmaceuticals, St. Louis, MO.

Escitalopram Oral Solution

Generic Name: escitalopram

Brand Name: Lexapro

Synonyms: Escitalopram

What is Escitalopram Oral Solution?