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Erythromycin and sulfisoxazole and Myasthenia gravis

Result of checking the interaction of drug Erythromycin and sulfisoxazole and disease Myasthenia gravis for safety when used together.

Check result:

Erythromycin and sulfisoxazole <> Myasthenia gravis

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of macrolide antibiotics has been reported to exacerbate symptoms of myasthenia gravis and trigger new onset of symptoms of myasthenic syndrome. Limited data suggest presynaptic suppression of acetylcholine release. Therapy with these agents should be administered cautiously in patients with a history of myasthenia gravis.

References:

May EF, Calvert PC "Aggravation of myasthenia gravis by erythromycin." Ann Neurol 28 (1990): 577-9
"Product Information. Ery-tab (erythromycin)." Abbott Pharmaceutical, Abbott Park, IL.

Erythromycin and sulfisoxazole

Generic Name: erythromycin / sulfisoxazole

Brand Name:

Synonyms: Erythromycin and sulfisoxazole (Oral), Erythromycin and Sulfisoxazole

What is Erythromycin and sulfisoxazole?