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Emend for Injection and QT prolongation

Result of checking the interaction of drug Emend for Injection and disease QT prolongation for safety when used together.

Check result:

Emend for Injection <> QT prolongation

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Fosaprepitant, a prodrug of aprepitant, is a weak inhibitor of CYP3A4, and aprepitant is a substrate, inhibitor, and inducer of CYP3A4. An increased plasma concentration of fosaprepitant could cause QT prolongation. Caution is advised in patients with long QT, and in patients receiving other drugs that are CYP3A4 substrates as it may result in a risk of higher plasma concentrations and adverse events. Close monitoring is recommended in these patients.

Emend for Injection

Generic Name: fosaprepitant

Brand Name: Emend for Injection

Synonyms: n.a.

What is Emend for Injection?