Drug search by name

Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir Disoproxil Fumarate and Creatinine clearance

Result of checking the interaction of drug Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir Disoproxil Fumarate and disease Creatinine clearance for safety when used together.

Check result:

Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir Disoproxil Fumarate <> Creatinine clearance

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Cobicistat has shown to decrease creatinine clearance without affecting actual renal glomerular function and no dose adjustment is required in patients with renal impairment, including those with severe renal impairment. However, this effect should be considered when interpreting changes in estimated creatinine clearance in patients initiating cobicistat when there is presence of renal impairment or in patients receiving other drugs that need to be monitored with estimated creatinine clearance. Patients who experience a confirmed increase of serum creatinine of 0.4 mg/dL from baseline should be closely monitored for renal safety.

Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir Disoproxil Fumarate

Generic Name: cobicistat / elvitegravir / emtricitabine / tenofovir

Brand Name: Genvoya, Stribild

Synonyms: Cobicistat, elvitegravir, emtricitabine, and tenofovir

What is Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir Disoproxil Fumarate?