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Eletriptan Hydrobromide and Liver disease

Generic Name: eletriptan
Dosage Forms: n.a.
Other Brand Names: Relpax

Result of checking the interaction of drug Eletriptan Hydrobromide and disease Liver disease for safety when used together.

Check result:

Eletriptan Hydrobromide <> Liver disease

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Eletriptan is primarily metabolized by the liver. In patients with mild to moderate hepatic impairment, increases of 18% in the peak plasma concentration (Cmax) and 34% in the systemic exposure (AUC) of eletriptan were observed. Dosage adjustments should not be necessary in this patient population. There are no data concerning the use of eletriptan in patients with severe hepatic impairment, thus it is not recommended.

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