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Efavirenz, lamivudine, and tenofovir and Mental symptoms

Generic Name: efavirenz / lamivudine / tenofovir
Dosage Forms: n.a.
Other Brand Names: Symfi , Symfi Lo

Result of checking the interaction of drug Efavirenz, lamivudine, and tenofovir and disease Mental symptoms for safety when used together.

Check result:

Efavirenz, lamivudine, and tenofovir <> Mental symptoms

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

During clinical trials, there have been infrequent reports of delusions and inappropriate behavior associated with the use of efavirenz, predominantly in patients with a history of mental illness or substance abuse. Severe acute depression, including suicide attempts and suicidal ideation, has also been reported but was not limited to efavirenz treated patients. Therapy with efavirenz should be administered cautiously in patients with a current or past history of psychiatric illness, emotional instability, or substance abuse. If symptoms develop or worsen during treatment, discontinuation of efavirenz may be necessary.

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