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Doxepin Tablets and Pheochromocytoma

Result of checking the interaction of drug Doxepin Tablets and disease Pheochromocytoma for safety when used together.

Check result:

Doxepin Tablets <> Pheochromocytoma

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Tricyclic and tetracyclic antidepressants (TCAs) may potentiate the effects of circulating catecholamines. Enhanced sympathetic activity can provoke hypertensive crises in patients with pheochromocytoma or other tumors of the adrenal medulla, such as some neuroblastomas. Therapy with TCAs should be administered cautiously in patients with these tumors.

References:

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"Product Information. Sinequan (doxepin)." Roerig Division, New York, NY.
"Product Information. Anafranil (clomipramine)." Basel Pharmaceuticals, Summit, NJ.
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"Product Information. Vivactil (protriptyline)" Merck & Co, Inc, West Point, PA.
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