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Doxepin Tablets and Anticholinergic effects

Result of checking the interaction of drug Doxepin Tablets and disease Anticholinergic effects for safety when used together.

Check result:

Doxepin Tablets <> Anticholinergic effects

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of doxepin is contraindicated in patients with glaucoma, or a tendency to urinary retention. These disorders should be ruled out before starting treatment, especially in elderly patients.

Doxepin Tablets

Generic Name: doxepin

Brand Name: Silenor, Sinequan, Sinequan

Synonyms: Doxepin (Sinequan), Doxepin (Systemic)

What is Doxepin Tablets?

Another drug Delete

Doxepin Tablets <> Anticholinergic effects

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

Consumer:

Tricyclic and tetracyclic antidepressants (TCAs) have anticholinergic activity, to which elderly patients are particularly sensitive. Tertiary amines such as amitriptyline and trimipramine tend to exhibit greater anticholinergic effects than other agents in the class. Therapy with TCAs should be administered cautiously in patients with preexisting conditions that are likely to be exacerbated by anticholinergic activity, such as urinary retention or obstruction; angle-closure glaucoma, untreated intraocular hypertension, or uncontrolled primary open-angle glaucoma; and gastrointestinal obstructive disorders. In patients with angle-closure glaucoma, even average doses can precipitate an attack. Glaucoma should be treated and under control prior to initiation of therapy with TCAs, and intraocular pressure monitored during therapy.

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