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Disopyramide Phosphate and Anticholinergic activity

Result of checking the interaction of drug Disopyramide Phosphate and disease Anticholinergic activity for safety when used together.

Check result:

Disopyramide Phosphate <> Anticholinergic activity

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Disopyramide has anticholinergic activity, and therapy with disopyramide should be administered with extreme caution in patients who may be adversely affected by this. Disopyramide should not be used in patients with glaucoma, myasthenia gravis, or urinary retention unless adequate overriding measures are taken.

References:

Ahmad S "Disopyramide: pulmonary complications and glaucoma." Mayo Clin Proc 65 (1990): 1030-1
Danziger LH, Horn JR "Disopyramide-induced urinary retention." Arch Intern Med 143 (1983): 1683-6
Teichman SL, Ferrick A, Kim SG, et al "Disopyramide-pyridostigmine interaction: selective reversal of anticholinergic symptoms with preservation of antiarrhythmic effect." J AM Coll Cardiol 10 (1987): 633-41
"Product Information. Norpace (disopyramide)." Searle, Skokie, IL.

Disopyramide Phosphate

Generic Name: disopyramide

Brand Name: Norpace, Norpace CR

Synonyms: Disopyramide

What is Disopyramide Phosphate?