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Diphenoxylate and Atropine Tablets and Fluid/electrolytes

Result of checking the interaction of drug Diphenoxylate and Atropine Tablets and disease Fluid/electrolytes for safety when used together.

Check result:
Diphenoxylate and Atropine Tablets <> Fluid/electrolytes
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Diarrhea can cause severe dehydration and electrolyte imbalance. Fluid accumulation within the GI track due to antiperistaltic-associated decrease in peristalsis can further aggravate dehydration and electrolyte imbalance. Antiperistaltic agents should be administered cautiously in patients with electrolyte imbalance and rehydration and electrolyte replacement should be initiated prior to initiation of therapy.

References:
  • "Product Information. Kaopectate (attapulgite)." Pharmacia and Upjohn, Kalamazoo, MI.
  • "Product Information. Pepto-Bismol (bismuth subsalicylate)." Procter and Gamble Pharmaceuticals, Cincinnati, OH.
  • "Product Information. Imodium (loperamide)." Janssen Pharmaceutica, Titusville, NJ.
Diphenoxylate and Atropine Tablets

Generic Name: atropine / diphenoxylate

Brand Name: Lomotil, Lonox, Lomocot, Vi-Atro

Synonyms: Atropine and diphenoxylate, Diphenoxylate and Atropine

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