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Dimetapp Long Acting Cough Plus Cold and Cardiovascular

Result of checking the interaction of drug Dimetapp Long Acting Cough Plus Cold and disease Cardiovascular for safety when used together.

Check result:
Dimetapp Long Acting Cough Plus Cold <> Cardiovascular
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Antihistamines may infrequently cause cardiovascular adverse effects related to their anticholinergic and local anesthetic (quinidine-like) activities. Tachycardia, palpitation, ECG changes, arrhythmias, hypotension, and hypertension have been reported. Although these effects are uncommon and usually limited to overdosage situations, the manufacturers and some clinicians recommend that therapy with antihistamines be administered cautiously in patients with cardiovascular disease, hypertension, and/or hyperthyroidism.

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  • "Product Information. Chlortrimeton (chlorpheniramine)." Schering-Plough, Liberty Corner, NJ.
  • "Product Information. Optimine (azatadine)." Schering Laboratories, Kenilworth, NJ.
  • "Product Information. Antivert (meclizine)." Roerig Division, New York, NY.
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  • "Product Information. Periactin (cyproheptadine)." Merck & Co, Inc, West Point, PA.
  • Smith SJ "Cardiovascular toxicity of antihistamines." Otolaryngol Head Neck Surg 111 Suppl (1994): 348-54
  • "Product Information. Zyrtec (cetirizine)." Pfizer US Pharmaceuticals, New York, NY.
  • "Product Information. Drixoral (dextromethorphan)." Schering-Plough, Liberty Corner, NJ.
  • Schuller DE, Turkewitz D "Adverse effects of antihistamines." Postgrad Med 79 (1986): 75-86
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  • "Product Information. Dramamine (dimenhydrinate)" Pharmacia and Upjohn, Kalamazoo, MI.
  • "Product Information. Poly-Histine-D (pyrilamine)." Bock Pharmaceutical Company, St. Louis, MO.
  • "Product Information. Vistaril (hydroxyzine)." Pfizer US Pharmaceuticals, New York, NY.
Dimetapp Long Acting Cough Plus Cold

Generic Name: chlorpheniramine / dextromethorphan

Brand Name: Children's NyQuil Cold & Cough, Coricidin HBP Cough & Cold, Dimetapp Long Acting Cough Plus Cold, Robitussin Pediatric Cough & Cold Long-Acting, Scot-Tussin Sugar Free DM, Triaminic Cough & Runny Nose, Effective Strength Cough Syrup, Primatuss 4, Coricidin HBP Cough and Cold, Tricodene Sugar Free, Triaminic Night Time Cough & Runny Nose, Triaminic Cough & Runny Nose Softchews, Robitussin Cough & Cold Long-Acting, Cough & Cold, Coricidin HBP Cough/Cold, QC Cough/Cold, Scot-Tussin DM, Tricodene SF

Synonyms: n.a.

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