Drug search by name

Dilantin and Porphyria

Result of checking the interaction of drug Dilantin and disease Porphyria for safety when used together.

Check result:

Dilantin <> Porphyria

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of phenytoin has rarely been associated with exacerbation of porphyria. Therapy with phenytoin should be administered cautiously in patients with porphyria. The same precaution should also be observed with other hydantoin anticonvulsants (i.e. ethotoin and mephenytoin) because of their structural and pharmacological similarities to phenytoin.

References:

Fauci AS, Braunwald E, Isselbacher KJ, Wilson JD, Martin JB, Kasper DL, Hauser SL, Longo DL, eds. "Harrison's Principles of Internal Medicine. 14th ed." New York, NY: McGraw-Hill Health Professionals Division (1998):
"Product Information. Cerebyx (fosphenytoin)." Parke-Davis, Morris Plains, NJ.
"Product Information. Dilantin (phenytoin)." Parke-Davis, Morris Plains, NJ.

Dilantin

Generic Name: phenytoin

Brand Name: Dilantin, Phenytek, Dilantin Infatabs, Phenytoin Sodium, Prompt

Synonyms: n.a.

What is Dilantin?