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Diflucan (Fluconazole Tablets) and Renal dysfunction

Result of checking the interaction of drug Diflucan (Fluconazole Tablets) and disease Renal dysfunction for safety when used together.

Check result:

Diflucan (Fluconazole Tablets) <> Renal dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Fluconazole is primarily eliminated by the kidney. Patients with renal impairment may be at greater risk for adverse effects from fluconazole due to decreased drug clearance. Dosage adjustments are recommended for patients with moderate to severe renal impairment (CrCl <= 50 mL/min) receiving multiple doses of the drug.

References:

Toon S, Ross CE, Gokal R, Rowland M "An assessment of the effects of impaired renal function and haemodialysis on the pharmacokinetics of fluconazole." Br J Clin Pharmacol 29 (1990): 221-6
"Product Information. Diflucan (fluconazole)." Roerig Division, New York, NY.
Debruyne D, Ryckelynck JP "Clinical pharmacokinetics of fluconazole." Clin Pharmacokinet 24 (1993): 10-27

Diflucan (Fluconazole Tablets)

Generic Name: fluconazole

Brand Name: Diflucan

Synonyms: Diflucan

What is Diflucan (Fluconazole Tablets)?