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Didanosine Delayed-Release Enteric-Coated Capsules and Bone marrow suppression

Result of checking the interaction of drug Didanosine Delayed-Release Enteric-Coated Capsules and disease Bone marrow suppression for safety when used together.

Check result:
Didanosine Delayed-Release Enteric-Coated Capsules <> Bone marrow suppression
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The nucleoside reverse transcriptase inhibitors, didanosine (ddI), zalcitabine (ddC) and stavudine (d4T), may infrequently cause bone marrow suppression at recommended dosages. Anemia, leukopenia, thrombocytopenia and neutropenia have been reported. Therapy with these agents should be administered cautiously in patients with preexisting bone marrow depression or blood dyscrasias. Routine blood counts are recommended.

References:
  • "Product Information. HIVID (zalcitabine)." Roche Laboratories, Nutley, NJ.
  • "Product Information. Videx (didanosine)." Bristol-Myers Squibb, Princeton, NJ.
  • "Product Information. Zerit (stavudine)." Bristol-Myers Squibb, Princeton, NJ.
Didanosine Delayed-Release Enteric-Coated Capsules

Generic Name: didanosine

Brand Name: Videx, Videx EC

Synonyms: Didanosine