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Dicloxacillin and Cystic fibrosis

Result of checking the interaction of drug Dicloxacillin and disease Cystic fibrosis for safety when used together.

Check result:

Dicloxacillin <> Cystic fibrosis

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The penicillinase-resistant penicillins, dicloxacillin and methicillin, are both eliminated by the kidney. Renal elimination of these penicillins has been shown to increase in patients with cystic fibrosis, resulting in decreased peak serum drug concentrations and AUCs. Clinicians should be cognizant of these effects when prescribing or administering the antibiotics to patients with cystic fibrosis.

References:

"Product Information. Dynapen (dicloxacillin)." Apothecon Inc, Plainsboro, NJ.
Yaffe SJ, Gerbracht LM, Mosovich LL, Mattar ME, Danish M, Jusko WJ "Pharmacokinetics of methicillin in patients with cystic fibrosis." J Infect Dis 135 (1977): 828-31
"Product Information. Staphcillin (methicillin)." Apothecon Inc, Plainsboro, NJ.

Dicloxacillin

Generic Name: dicloxacillin

Brand Name: Dycill, Dynapen

Synonyms: n.a.

What is Dicloxacillin?