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Akynzeo (Netupitant and Palonosetron) and Renal impairment

Result of checking the interaction of drug Akynzeo (Netupitant and Palonosetron) and disease Renal impairment for safety when used together.

Check result:

Akynzeo (Netupitant and Palonosetron) <> Renal impairment

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Population pharmacokinetic analysis showed that mild and moderate renal impairment (creatinine clearance 30 to 60 mL/min) did not significantly affect the pharmacokinetics of netupitant. The pharmacokinetics and safety of netupitant have not been studied in patients with severe renal impairment. Avoid use in patients with severe renal impairment or end-stage renal disease.

Akynzeo (Netupitant and Palonosetron)

Generic Name: netupitant / palonosetron

Brand Name: Akynzeo

Synonyms: Akynzeo

What is Akynzeo (Netupitant and Palonosetron)?