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Dexamethasone injection and Scleroderma

Result of checking the interaction of drug Dexamethasone injection and disease Scleroderma for safety when used together.

Check result:

Dexamethasone injection <> Scleroderma

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

In patients with scleroderma, corticosteroids may precipitate renal crisis with malignant hypertension, possibly via steroid-induced increases in renin substrate and angiotensin II levels and decreases in vasodilator prostaglandin production. Renal failure may ensue. Therapy with corticosteroids should be administered cautiously in patients with scleroderma. In addition, they should be limited to short-term use.

References:

"Product Information. Decadron (dexamethasone)." Merck & Co, Inc, West Point, PA.
"Product Information. Deltasone (prednisone)." Pharmacia and Upjohn, Kalamazoo, MI.
"Product Information. Medrol (methylprednisolone)." Pharmacia and Upjohn, Kalamazoo, MI.
"Product Information. Celestone (betamethasone)." Schering Corporation, Kenilworth, NJ.
Fauci AS, Braunwald E, Isselbacher KJ, Wilson JD, Martin JB, Kasper DL, Hauser SL, Longo DL, eds. "Harrison's Principles of Internal Medicine. 14th ed." New York, NY: McGraw-Hill Health Professionals Division (1998):
"Product Information. Florinef Acetate (fludrocortisone)." Bristol-Myers Squibb, Princeton, NJ.
"Product Information. Kenalog (triamcinolone)." Bristol-Myers Squibb, Princeton, NJ.
"Product Information. Hydeltrasol (prednisolone)." Merck & Co, Inc, West Point, PA.
"Product Information. Hydrocortone (hydrocortisone)." Merck & Co, Inc, West Point, PA.
"Product Information. Cortone Acetate (cortisone)." Merck & Co, Inc, West Point, PA.

Dexamethasone injection

Generic Name: dexamethasone

Brand Name: Baycadron, Decadron, Dexamethasone Intensol, DexPak, TaperDex, Zema-Pak, ZoDex, Zonacort, DexPak 10 Day Taperpak, DexPak 13 DayTaperpak, DexPak 6 DayTaperpak, De-Sone LA, Dexacen-4, Dexasone, Dexasone LA, Solurex, Solurex LA

Synonyms: Dexamethasone, Dexamethasone (Systemic)

What is Dexamethasone injection?