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Demeclocycline and Diabetes insipidus syndrome

Result of checking the interaction of drug Demeclocycline and disease Diabetes insipidus syndrome for safety when used together.

Check result:

Demeclocycline <> Diabetes insipidus syndrome

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of demeclocycline has been associated with a dose-dependent, reversible, nephrogenic diabetes insipidus syndrome in some patients receiving long-term therapy. Symptoms of diabetes insipidus include polyuria, polydipsia, and weakness. Therapy with demeclocycline should be administered cautiously in patients with preexisting nephrogenic diabetes insipidus.

References:

Cherrill DA, Stote RM, Birge JR, Singer I "Demeclocycline treatment in the syndrome of inappropriate antidiuretic hormone secretion." Ann Intern Med 83 (1975): 654-6
"Product Information. Declomycin (demeclocycline)." Lederle Laboratories, Wayne, NJ.
Perks WH, Walters EH, Tams IP, Prowse K "Demeclocycline in the treatment of the syndrome of inappropriate secretion of antidiuretic hormone." Thorax 34 (1979): 324-7
Braden GL, Geheb MA, Shook A, Singer I, Cox M "Demeclocycline-induced natriuresis and renal insufficiency: in vivo and in vitro studies." Am J Kidney Dis 5 (1985): 270-7
Singer I, Rotenberg D "Demeclocycline-induced nephrogenic diabetes insipidus. In-vivo and in- vitro studies." Ann Intern Med 79 (1973): 679-83
Hayek A, Ramirez J "Demeclocycline-induced diabetes insipidus." JAMA 229 (1974): 676-7

Demeclocycline

Generic Name: demeclocycline

Brand Name: Declomycin

Synonyms: n.a.

What is Demeclocycline?