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Darunavir, Cobicistat, Emtricitabine, and Tenofovir Alafenamide Fumarate and Bone toxicity

Result of checking the interaction of drug Darunavir, Cobicistat, Emtricitabine, and Tenofovir Alafenamide Fumarate and disease Bone toxicity for safety when used together.

Check result:
Darunavir, Cobicistat, Emtricitabine, and Tenofovir Alafenamide Fumarate <> Bone toxicity
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Osteomalacia and reduced bone mineral density have been reported in animal toxicology studies involving tenofovir exposures 6- to 12-fold those observed in humans. The mechanism of bone toxicity has not been established, and it is not known if long-term use of tenofovir disoproxil fumarate will cause bone abnormalities in humans.

References:
  • "Product Information. Viread (tenofovir)." Gilead Sciences, Foster City, CA.
Darunavir, Cobicistat, Emtricitabine, and Tenofovir Alafenamide Fumarate

Generic Name: cobicistat / darunavir / emtricitabine / tenofovir alafenamide

Brand Name: Symtuza

Synonyms: Cobicistat, darunavir, emtricitabine, and tenofovir, Darunavir, Cobicistat, Emtricitabine, and Tenofovir Alafenamide

What is Darunavir, Cobicistat, Emtricitabine, and Tenofovir Alafenamide Fumarate?
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