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Darunavir and Cobicistat and Hepatotoxicity

Result of checking the interaction of drug Darunavir and Cobicistat and disease Hepatotoxicity for safety when used together.

Check result:

Darunavir and Cobicistat <> Hepatotoxicity

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Drug-induced hepatitis has been reported with the use of darunavir/ritonavir. Patients with underlying liver disease including chronic active hepatitis B or C viral infections have an increased risk for liver function abnormalities. Therapy with darunavir should be administered cautiously in patients with preexisting liver disease, liver enzyme abnormalities, or hepatitis. The combination of darunavir/ritonavir is not recommended for use in patients with severe hepatic impairment.

Darunavir and Cobicistat

Generic Name: cobicistat / darunavir

Brand Name: Prezcobix

Synonyms: Cobicistat and darunavir

What is Darunavir and Cobicistat?