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Cytarabine (Conventional) and Hepatic dysfunction

Result of checking the interaction of drug Cytarabine (Conventional) and disease Hepatic dysfunction for safety when used together.

Check result:
Cytarabine (Conventional) <> Hepatic dysfunction
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Cytarabine is extensively metabolized by the liver. Patients with impaired hepatic function may be at increased risk for CNS toxicity during high dose cytarabine therapy. Therapy with cytarabine should be administered cautiously and the dosages modified in patients with or predisposed to compromised hepatic function. Periodic checks of liver function should be performed in patients receiving Cytarabine Injection.

References:
  • "Product Information. Cytosar-U (cytarabine)." Pharmacia and Upjohn, Kalamazoo, MI.
Cytarabine (Conventional)

Generic Name: cytarabine

Brand Name: Cytosar-U, Tarabine PFS, Cytosar

Synonyms: Cytarabine

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