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Cyclobenzaprine and Anticholinergic effects

Result of checking the interaction of drug Cyclobenzaprine and disease Anticholinergic effects for safety when used together.

Check result:

Cyclobenzaprine <> Anticholinergic effects

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Cyclobenzaprine has anticholinergic activity, to which elderly patients are particularly sensitive. Therapy with cyclobenzaprine should be administered cautiously in patients with preexisting conditions that are likely to be exacerbated by anticholinergic activity, such as urinary retention or obstruction; angle-closure glaucoma, untreated intraocular hypertension, or uncontrolled primary open-angle glaucoma; and gastrointestinal obstructive disorders. Glaucoma should be treated and under control prior to initiation of cyclobenzaprine therapy, and intraocular pressure monitored during therapy.

References:

Heckerling PS, Bartow TJ "Paradoxical diaphoresis in cyclobenzaprine poisoning." Ann Intern Med 101 (1984): 881
Linden CH, Mitchiner JC, Lindzon RD, Rumack BH "Cyclobenzaprine overdosage." J Toxicol Clin Toxicol 20 (1983): 281-8
"Product Information. Flexeril (cyclobenzaprine)." Merck & Co, Inc, West Point, PA.

Cyclobenzaprine

Generic Name: cyclobenzaprine

Brand Name: Amrix, Comfort Pac with Cyclobenzaprine, Fexmid, Flexeril

Synonyms: n.a.

What is Cyclobenzaprine?