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Corticorelin ovine triflutate and Osteoporosis

Result of checking the interaction of drug Corticorelin ovine triflutate and disease Osteoporosis for safety when used together.

Check result:

Corticorelin ovine triflutate <> Osteoporosis

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Adrenocorticotropic agents inhibit the absorption of intestinal calcium and increase urinary excretion of calcium, which can result in bone resorption and bone loss during prolonged therapy. In addition, bone matrix may be affected by the protein-catabolic effects of these agents, especially when given in high dosages or for prolonged periods, leading to aseptic necrosis and fractures. Long-term or high-dose adrenocorticotropic therapy should be administered cautiously and only if necessary in patients with or at risk for osteoporosis. The manufacturers consider the use of adrenocorticotropic agents to be contraindicated in such setting.

References:

"Product Information. Acthar (corticotropin)." Rhone-Poulenc Rorer, Collegeville, PA.
"Product Information. Acthrel (corticorelin)." Ferring Laboratories Inc, Tarrytown, NY.
"Product Information. Cortrosyn (cosyntropin)" Organon, West Orange, NJ.

Corticorelin ovine triflutate

Generic Name: corticorelin

Brand Name: Acthrel

Synonyms: n.a.

What is Corticorelin ovine triflutate?