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Conivaptan Intravenous and Liver disease/alcoholism

Result of checking the interaction of drug Conivaptan Intravenous and disease Liver disease/alcoholism for safety when used together.

Check result:
Conivaptan Intravenous <> Liver disease/alcoholism
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Osmotic demyelination syndrome is a risk associated with overly rapid correction of hyponatremia (> 12 mEq/L/24 hours). This syndrome can result in dysarthria, mutism, dysphagia, lethargy, affective changes, spastic quadriparesis, seizure, coma or death. Patients with advanced liver disease, alcoholism or severe malnutrition are at increased risk and require slower rates of correction. Serum sodium concentration and neurological status should be monitored appropriately during treatment administration. Vasopressin antagonists should be initiated and re- initiated in patients only in hospital settings were sodium levels can be monitored closely.

Conivaptan Intravenous

Generic Name: conivaptan

Brand Name: Vaprisol

Synonyms: Conivaptan

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