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Cobimetinib and Hepatotoxicity

Result of checking the interaction of drug Cobimetinib and disease Hepatotoxicity for safety when used together.

Check result:
Cobimetinib <> Hepatotoxicity
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Hepatotoxicity can occur with the use of cobimetinib. It is recommended to monitor liver function tests before initiation of therapy, monthly during treatment, or more frequently as clinically indicated. Manage Grade 3 and 4 liver laboratory abnormalities with dose interruption, reduction, or discontinuation of therapy. Close monitoring is recommended.

Cobimetinib

Generic Name: cobimetinib

Brand Name: Cotellic

Synonyms: n.a.

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