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Clozapine Oral Suspension and CNS depression

Result of checking the interaction of drug Clozapine Oral Suspension and disease CNS depression for safety when used together.

Check result:
Clozapine Oral Suspension <> CNS depression
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

The use of neuroleptic agents is contraindicated in comatose patients and patients with severe central nervous system depression. Neuroleptic agents may potentiate the CNS and respiratory depression in these patients.

References:
  • "Product Information. Haldol (haloperidol)." McNeil Pharmaceutical, Raritan, NJ.
  • "Product Information. Navane (thiothixene)." Roerig Division, New York, NY.
  • "Product Information. Orap Tablets (pimozide)." Gate Pharmaceuticals, Sellersville, PA.
  • "Product Information. Loxitane C Oral Concentrate (loxapine)" Watson Laboratories Inc, Corona, CA.
  • "Product Information. Moban (molindone)." Gate Pharmaceuticals, Sellersville, PA.
  • Vetter PH, Proppe DG "Clozapine-induced coma." J Nerv Ment Dis 180 (1992): 58-9
  • "Product Information. Clozaril (clozapine)." Novartis Pharmaceuticals, East Hanover, NJ.
Clozapine Oral Suspension

Generic Name: clozapine

Brand Name: Clozaril, Fazaclo, Versacloz, Clopine, CloZAPine Synthon, Denzapine, Zaponex

Synonyms: Clozapine, CloZAPine

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