Clofibrate and Cardiovascular effects
Result of checking the interaction of drug Clofibrate and disease Cardiovascular effects for safety when used together.
When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.
Consumer:The use of clofibrate has been associated with an increased incidence of adverse cardiovascular effects, including cardiac arrhythmias, intermittent claudication, thromboembolic events, and angina. Because of these risks, as well as the lack of substantial evidence demonstrating a beneficial effect on cardiovascular mortality, therapy with clofibrate should be considered and administered cautiously in patients with a history of cardiovascular or cerebrovascular disease.
- "Product Information. Atromid-S (clofibrate)." Wyeth-Ayerst Laboratories, Philadelphia, PA.