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Adrucil and Bleeding

Generic Name: fluorouracil
Dosage Forms: injection, solution
Other Brand Names: Adrucil

Result of checking the interaction of drug Adrucil and disease Bleeding for safety when used together.

Check result:

Adrucil <> Bleeding

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Fluorouracil (5- FU) induces myelosuppression, including thrombocytopenia. Therapy with 5- FU should be administered cautiously in patients with bleeding tendencies. Therapy with 5- FU should be promptly discontinued following bleeding from any sight. Patients should be instructed to immediately report any signs or symptoms suggesting bleeding such as petechiae, purpura, hematuria, or melena. Close clinical monitoring of hematopoietic function is recommended. Therapy with 5- FU should be withheld if platelet counts falls below 100,000/mm3.

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