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Cholestyramine Light and Hyperchloremia

Result of checking the interaction of drug Cholestyramine Light and disease Hyperchloremia for safety when used together.

Check result:
Cholestyramine Light <> Hyperchloremia
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Bile acid sequestrants are chloride forms of anion exchange resins and may produce hyperchloremic acidosis with chronic use. Therapy with bile acid sequestrants should be administered cautiously in patients who may be particularly susceptible, including children or smaller patients and patients with renal impairment or volume depletion.

References:
  • Kleinman PK "Letter: Cholestyramine and metabolic acidosis." N Engl J Med 290 (1974): 861
  • "Product Information. Questran (cholestyramine)." Par Pharmaceutical Inc, Chestnut Ridge, NY.
  • "Product Information. Colestid (colestipol HCI)." Pharmacia and Upjohn, Kalamazoo, MI.
  • Clouston WM, Lloyd HM "Cholestyramine induced hyperchloremic metabolic acidosis ." Aust N Z J Med 15 (1985): 271
  • Eaves ER, Korman MG "Cholestyramine induced hyperchloremic metabolic acidosis." Aust N Z J Med 14 (1984): 670-2
  • Scheel PJ Jr, Whelton A, Rossiter K, Watson A "Cholestyramine-induced hyperchloremic metabolic acidosis." J Clin Pharmacol 32 (1992): 536-8
  • Hartline JV "Letter: Hyperchloremia, metabolic acidosis, and cholestyramine." J Pediatr 89 (1976): 155
Cholestyramine Light

Generic Name: cholestyramine

Brand Name: Cholestyramine Light, Prevalite, Questran, Questran Light, Locholest, Locholest Light, Questran Light Packets, Prevalite Packets, Questran Packets

Synonyms: n.a.

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