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Chlorpheniramine, Pseudoephedrine, and Dextromethorphan and PKU

Result of checking the interaction of drug Chlorpheniramine, Pseudoephedrine, and Dextromethorphan and disease PKU for safety when used together.

Check result:
Chlorpheniramine, Pseudoephedrine, and Dextromethorphan <> PKU
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Chewable products frequently may contain aspartame, which is metabolized in the gastrointestinal tract to phenylalanine. Sudafed (brand of pseudoephedrine) chewable 15 mg tablets provide the equivalent of 0.78 mg of phenylalanine per each tablet. The aspartame/phenylalanine content should be considered when this and similar products are used in patients who must restrict their intake of phenylalanine (i.e. phenylketonurics).

References:
  • "Product Information. Sudafed (pseudoephedrine)." Glaxo Wellcome, Research Triangle Park, NC.
Chlorpheniramine, Pseudoephedrine, and Dextromethorphan

Generic Name: chlorpheniramine / dextromethorphan / pseudoephedrine

Brand Name: Kidkare Cough/Cold, Pediatric Cough & Cold Medicine, Rescon-DM, Triaminic Cold and Cough, Vicks Pediatric Formula 44M, Triaminic Night Time, Rhinosyn-DM, Pediacare Nightrest, Pediacare Cough-Cold Chewable, Robitussin Pediatric Night Relief, Vicks 44M Pediatric, Creomulsion Cough/Cold/Allergy, Nyquil Child Cough and Cold, Creomulsion Pediatric, Pediacare Cough and Cold, Childrens Night Time, Children's NyQuil, Triaminic Softchew Cold and Cough, Tanafed-DM, C-Phed DM, T-Tanna-DM, M-End DM, Atuss-12 DM, Robitussin PM Cough & Cold, Dicel DM, Atuss DS, Neutrahist PDX Drops, AccuHist PDX Drops, Triaminic Multi-Sympton, Allres DS, Triaminic-D Multi-Symptom Cold, Entre-S, Dicel DM Chewables, Mesehist DM, Esocor P, Kidkare Children's Cough/Cold, Maxichlor PSE DM, Pedia Relief Cough-Cold, Pediatric Cough & Cold, Rescon DM

Synonyms: Chlorpheniramine, dextromethorphan, and pseudoephedrine