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Chlorpheniramine, methscopolamine, and phenylephrine and Glaucoma

Result of checking the interaction of drug Chlorpheniramine, methscopolamine, and phenylephrine and disease Glaucoma for safety when used together.

Check result:

Chlorpheniramine, methscopolamine, and phenylephrine <> Glaucoma

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Anticholinergic agents are contraindicated in patients with primary glaucoma, a tendency toward glaucoma (narrow anterior chamber angle), or adhesions (synechiae) between the iris and lens, as well as for the elderly and others in whom undiagnosed glaucoma or excessive pressure in the eye may be present. Because anticholinergics cause mydriasis, they may exacerbate these conditions.

References:

"Product Information. Chlortrimeton (chlorpheniramine)." Schering-Plough, Liberty Corner, NJ.
"Product Information. Moban (molindone)." Gate Pharmaceuticals, Sellersville, PA.
Schuller DE, Turkewitz D "Adverse effects of antihistamines." Postgrad Med 79 (1986): 75-86
"Product Information. Phenergan (promethazine)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
Goldstein JH "Effects of drugs on cornea, conjunctiva, and lids." Int Ophthalmol Clin 11 (1971): 13-34
"Product Information. Poly-Histine-D (pyrilamine)." Bock Pharmaceutical Company, St. Louis, MO.
Holland MG "Autonomic drugs in ophthalmology: some problems and promises. Section II: Anticholinergic drugs." Ann Ophthalmol 6 (1974): 661-4
Clearkin LG "Angle closure glaucoma precipitated by atropine." Arch Intern Med 152 (1992): 880
"Product Information. Thorazine (chlorpromazine)." SmithKline Beecham, Philadelphia, PA.
"Product Information. Benadryl (diphenhydramine)." Parke-Davis, Morris Plains, NJ.
O'Connor PS, Mumma JV "Atropine toxicity." Am J Ophthalmol 99 (1985): 613-4
Berdy GJ, Berdy SS, Odin LS, Hirst LW "Angle closure glaucoma precipitated by aerosolized atropine." Arch Intern Med 151 (1991): 1658-60
"Product Information. Artane (trihexyphenidyl)." Lederle Laboratories, Wayne, NJ.
"Product Information. Periactin (cyproheptadine)." Merck & Co, Inc, West Point, PA.
"Product Information. Atropine Sulfate Injection, USP (atropine)." ESI Lederle Generics, Philadelphia, PA.
"Product Information. Cogentin (benztropine)." Merck & Co, Inc, West Point, PA.
"Product Information. Dimetane (brompheniramine)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
Pecora JL "Malignant glaucoma worsened by miotics in a postoperative angle- closure glaucoma patient." Ann Ophthalmol 11 (1979): 1412-4
"Product Information. Compazine (prochlorperazine)." SmithKline Beecham, Philadelphia, PA.
"Product Information. Orap Tablets (pimozide)." Gate Pharmaceuticals, Sellersville, PA.
"Product Information. Optimine (azatadine)." Schering Laboratories, Kenilworth, NJ.
Kanto J "New aspects in the use of atropine." Int J Clin Pharmacol Ther Toxicol 21 (1983): 92-4
"Product Information. Tavist (clemastine)." Sandoz Pharmaceuticals Corporation, East Hanover, NJ.

Chlorpheniramine, methscopolamine, and phenylephrine

Generic Name: chlorpheniramine / methscopolamine / phenylephrine

Brand Name: AH-Chew II, Extendryl JR, Sinodec, Extendryl SR, Prehist D, Dallergy, Extendryl Syrup, Extendryl Chews, Ah-Chew, DA. Chewable, Omnihist LA, Dura-Vent/DA, Hista-Vent DA, DA. II, Liqui-Allergy, Duradryl, Duradryl JR, Drize, Drysec, Ex-Histine, WE Allergy, Chlor-Mes D, Norel SD, Durahist PE, PCM, Omnihist II LA, Ralix, Rescon MX, Aerohist Plus, Denaze, Aerokid, Dallergy ER, Phenylephrine CM, Extendryl Seniors, Dallergy Syrup, DuraTan PE, QV-Allergy, Rescon, AlleRx PE Dose Pack, Redur-PCM, Ah-Chew Ultra, Histatab PH, Chlor-Mes, PCM Allergy, Re-Drylex Jr, CPM-PE-MSC, Triall, SymPak PDX, ScopoHist-PE, Dehistine, DriHist SR, Nohist Plus, Nohist Plus Jr, Dallergy PE, Ah-Chew Ultra Tannate, Duravent, ScopoHist Syrup, Duradryl SR, Duravent-DA, Duradryl Chewable, Allergy DN PE, RelCof PE, RelCof DN PE, Nohist PE

Synonyms: n.a.

What is Chlorpheniramine, methscopolamine, and phenylephrine?

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Chlorpheniramine, methscopolamine, and phenylephrine <> Glaucoma

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

Consumer:

Sympathomimetic agents can induce transient mydriasis via stimulation of alpha-1 adrenergic receptors. In patients with anatomically narrow angles or narrow-angle glaucoma, pupillary dilation can provoke an acute attack. In patients with other forms of glaucoma, mydriasis may occasionally increase intraocular pressure. Therapy with sympathomimetic agents should be administered cautiously in patients with or predisposed to glaucoma, particularly narrow-angle glaucoma.

References:

Covington TR, Lawson LC, Young LL, eds. "Handbook of Nonprescription Drugs. 10th ed." Washington, DC: American Pharmaceutical Association (1993):
Fraunfelder FT, Fraunfelder FW; Randall JA "Drug-Induced Ocular Side Effects 5th" Boston, MA: Butterworth-Heinemann (2001):
"Product Information. Sudafed (pseudoephedrine)." Glaxo Wellcome, Research Triangle Park, NC.

Chlorpheniramine, methscopolamine, and phenylephrine

Generic Name: chlorpheniramine / methscopolamine / phenylephrine

Synonyms: n.a.

What is Chlorpheniramine, methscopolamine, and phenylephrine?

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