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Chlorpheniramine and codeine polistirex and Gastrointestinal obstruction

Result of checking the interaction of drug Chlorpheniramine and codeine polistirex and disease Gastrointestinal obstruction for safety when used together.

Check result:

Chlorpheniramine and codeine polistirex <> Gastrointestinal obstruction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Patients with gastrointestinal obstruction, particularly paralytic ileus, should generally not be given sustained-release oral formulations of narcotic analgesics. Opioid agents are is contraindicated in patients with known or suspected gastrointestinal obstruction, including paralytic ileus. In such patients, the ingested drug may remain in the stomach for an extended period of time, then released suddenly as a bolus when normal gut motility is restored, thereby increasing the risk for adverse effects and/or an overdose.

References:

"Product Information. OxyContin (oxycodone)." Purdue Frederick Company, Norwalk, CT.
"Product Information. Kadian (morphine)." Zeneca Pharmaceuticals, Wilmington, DE.

Chlorpheniramine and codeine polistirex

Generic Name: chlorpheniramine / codeine

Brand Name: Codar AR, Tuzistra XR, Codeprex, Cotab A, Cotab AX, Notuss-AC, Z-Tuss AC, Zodryl AC 25, Zodryl AC 30, Zodryl AC 35, Zodryl AC 50, Zodryl AC 40, Zodryl AC 60, Zodryl AC 80, EndaCof-C, TL-Hist CM, Zodryl AC Adult, Lexuss 210, EndaCof-C, Tuxarin ER

Synonyms: Chlorpheniramine and codeine, Codeine and Chlorpheniramine

What is Chlorpheniramine and codeine polistirex?