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Chloroquine and Seizures

Result of checking the interaction of drug Chloroquine and disease Seizures for safety when used together.

Check result:

Chloroquine <> Seizures

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

4-aminoquinolines may cause epileptic seizures in susceptible individuals. Patients with epilepsy or an otherwise low seizure threshold may be at greater risk. Therapy with 4-aminoquinolines, particularly chloroquine, should be administered cautiously in patients with epilepsy.

References:

Fish DR, Espir ML "Convulsions associated with prophylactic antimalarial drugs: implications for people with epilepsy." Br Med J 297 (1988): 526-7
Benbadis SR, Vanness PC "Chloroquine and nonconvulsive status epilepticus." Ann Intern Med 124 (1996): 614
"Product Information. Aralen (chloroquine)." Sanofi Winthrop Pharmaceuticals, New York, NY.
"Product Information. Plaquenil (R). (hydroxychloroquine)." Sanofi Winthrop Pharmaceuticals, New York, NY.
Mulhauser P, Allemann Y "Chloroquine and nonconvulsive status epilepticus." Ann Intern Med 123 (1995): 76-7

Chloroquine

Generic Name: chloroquine

Brand Name: Aralen Phosphate, Aralen Hydrochloride

Synonyms: n.a.

What is Chloroquine?