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Adcirca and Renal dysfunction
Result of checking the interaction of drug Adcirca and disease Renal dysfunction for safety when used together.
Check result:
Adcirca <> Renal dysfunction
Relevance: 23.07.2019
Reviewer: Shkutko P.M., M.D., in
When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.
Consumer:The plasma clearance of phosphodiesterase-5 (PDE5) inhibitors may be decreased in patients with severe renal impairment, resulting in drug accumulation. Therapy with these agents should be avoided in patients with severe renal disease or on renal dialysis. Dose adjustments might be needed based on individual renal assessment and tolerability if used in these patients.
References:
- "Product Information. Viagra (sildenafil)." Pfizer US Pharmaceuticals, New York, NY.
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