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Cardioquin and Renal dysfunction

Result of checking the interaction of drug Cardioquin and disease Renal dysfunction for safety when used together.

Check result:

Cardioquin <> Renal dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Renal dysfunction causes a slowed elimination of quinidine which can lead to quinidine toxicity if dosage is not appropriately reduced. Therapy with quinidine should be administered cautiously and dosages reduced in patients with compromised renal function. Quinidine is not appreciably removed by hemodialysis.

References:

Chin TW, Pancorbo S, Comty C "Quinidine pharmacokinetics in continuous abulatory peritoneal dialysis." Clin Exp Dial Apheresis 5 (1981): 391-7
Woie L, Oyri A "Quinidine intoxication treated with hemodialysis." Acta Med Scand 195 (1974): 237-9
Kessler KM, Lowenthal DT, Warner H, et al "Quinidine elimination in patients with congestive heart failure or poor renal function." N Engl J Med 290 (1974): 706-9
"Product Information. Quinidex (quinidine)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
Kessler KM, Perez GO "Decreased quinidine plasma protein binding during hemodialysis." Clin Pharmacol Ther 30 (1981): 121-6
Reimold EW, Reynolds WJ, Fixler DE, McElroy L "Use of hemodialysis in the treatment of quinidine poisoning." Pediatrics 52 (1973): 95-9
Quin J, Adamski M, Howlin K, et al "Quinidine-induced allergic granulomatous angiitis: an unusual cause of acute renal failure." Med J Aust 148 (1988): 145-6
Perez-Mateo M, Erill S "Protein binding of salicylate and quinidine in plasma from patients with renal failure, chronic liver disease and chronic respiratory insufficiency." Eur J Clin Pharmacol 11 (1977): 225-31
Bellet S, Roman LR, Boza A "Relation between serum quinidine levels and renal function." Am J Cardiol 27 (1971): 368-71
Levy R, Sellers A, Mandel WJ, et al "Quinidine pharmacokinetics in anephric and normal subjects (abstract)." Clin Res 24 (1976): a85

Cardioquin

Generic Name: quinidine

Brand Name: Quin-G, Cardioquin, Quinora, Quinidex Extentabs, Quinaglute Dura-Tabs, Quin-Release

Synonyms: n.a.

What is Cardioquin?