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Carboplatin and Renal dysfunction

Generic Name: carboplatin
Dosage Forms: n.a.
Other Brand Names: Paraplatin , CARBOplatin Novaplus

Result of checking the interaction of drug Carboplatin and disease Renal dysfunction for safety when used together.

Check result:

Carboplatin <> Renal dysfunction

Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Carboplatin is primarily eliminated by the kidney. Total body and renal clearance of carboplatin are reduced in patients with a creatinine clearance < 60 mL/min. Patients with impaired renal function are at increased risk for toxicity, particularly myelosuppression. Therapy with carboplatin should be administered cautiously in patients with compromised renal function. Clinical monitoring of renal function is recommended.

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