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Captopril and Hydrochlorothiazide and Thyroid function tests

Result of checking the interaction of drug Captopril and Hydrochlorothiazide and disease Thyroid function tests for safety when used together.

Check result:
Captopril and Hydrochlorothiazide <> Thyroid function tests
Relevance: 23.07.2019 Reviewer: Shkutko P.M., M.D., in

When checking interaction based on authoritative sources Drugs.com, Rxlist.com, Webmd.com, Medscape.com there are contraindications or side effects that may cause harm or increase the negative effect from drug use in presence of concomitant diseases.

Consumer:

Thiazide diuretics may decrease serum PBI (protein-bound iodine) levels without associated thyroid disturbance. Clinicians should be cognizant of this effect when prescribing or administering thiazide therapy to patients with thyroid disorders.

References:
  • Bech K, Skovsted L, Siersbaek-Nielsen K, Hansen JM "Influence of thiazides on thyroid parameters in man." Acta Endocrinol (Copenh) 89 (1978): 673-8
  • "Product Information. Thalitone (chlorthalidone)." Monarch Pharmaceuticals Inc, Bristol, TN.
  • "Product Information. Renese-R (reserpine-polythiazide)." Pfizer US Pharmaceuticals, New York, NY.
  • "Product Information. Zaroxolyn (metolazone)." Rhone-Poulenc Rorer, Collegeville, PA.
  • "Product Information. Metahydrin (trichlormethiazide)." Hoechst Marion-Roussel Inc, Kansas City, MO.
  • "Product Information. HydroDIURIL (hydrochlorothiazide)." Merck & Co, Inc, West Point, PA.
  • "Product Information. Diucardin (hydroflumethiazide)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
  • "Product Information. Diuril (chlorothiazide)." Merck & Co, Inc, West Point, PA.
  • "Product Information. Enduron (methyclothiazide)." Abbott Pharmaceutical, Abbott Park, IL.
  • "Product Information. Lozol (indapamide)." Rhone-Poulenc Rorer, Collegeville, PA.
Captopril and Hydrochlorothiazide

Generic Name: captopril / hydrochlorothiazide

Brand Name: Capozide 25/15, Capozide 25/25, Capozide 50/15, Capozide 50/25

Synonyms: Hydrochlorothiazide and captopril

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